Domashneva I V, Shapiro Iu A, Gindilis V M
Zh Nevropatol Psikhiatr Im S S Korsakova. 1981;81(3):394-6.
A genetic analysis of the immunological disturbances observed in patients with schizophrenic psychoses and registered from the level of the serum antilymphocytic activity was carried out. The analysis has shown that the contribution of genetic factors to the determination of interindividual differences in that feature exceeds more than twice the contribution of environmental factors. The close correlation between the serum antilymphocytic activity and the genetic component of the predisposition to the disease gives one grounds to regard a rise of the serum antilymphocytic activity as a pathogenetic marker of hereditary predisposition to schizophrenia. The results obtained, if taken together with literary data, may be of interest for studies concerned with the multicomponent structure of the hereditary predisposition to schizophrenic psychoses and their pathogenesis.
