Buchanan W, Sehgal P, Bronson R T, Rodger R F, Horton J E
Oral Surg Oral Med Oral Pathol. 1981 Jul;52(1):19-22. doi: 10.1016/0030-4220(81)90166-3.
A lesion in Macaca cyclopis which appears to conform to defined characteristics of noma in human beings has been reported. Clinical features in common include the gangrenous appearance of the lesion, the association with necrotizing ulcerative gingivitis, and the massive destruction of soft tissue and bone in the oronasofacial regions. Systemic features in common include debilitation of the host, leukocytosis, and depression of cellular immunologic responses. Microbiologic studies revealed the presence of organisms commonly found in necrotizing ulcerative gingivitis. The detection of true noma in nonhuman primates may now allow the opportunity for study of the etiology, pathophysiology, and therapy of this condition for human benefit.
据报道，台湾猕猴身上出现了一种病变，似乎符合人类走马疳的明确特征。共同的临床特征包括病变部位的坏疽外观、与坏死性溃疡性龈炎的关联，以及口鼻腔面部区域软组织和骨骼的大量破坏。共同的全身特征包括宿主衰弱、白细胞增多和细胞免疫反应抑制。微生物学研究发现了坏死性溃疡性龈炎中常见的微生物。在非人类灵长类动物中检测到真正的走马疳，现在可能为研究这种疾病的病因、病理生理学和治疗方法提供机会，以造福人类。
