Vargervik K
Cleft Palate J. 1981 Oct;18(4):256-70.
Experimental and clinical findings indicate that unfavorable adaptations of normal structures occur in children with clefts. It is postulated that these deviations from normal development are reversible and can be corrected or prevented by properly designed treatment. On this basis, five hypotheses were formulated and tested on the data from the subjects included in this study. The subjects consisted of 1) 16 children without clefts, 2) eight children who had complete unilateral clefts of the lip and palate but who had not received orthodontic treatment, and 3) 16 children who had complete unilateral clefts of the lip and palate and who had been treated by the described orthodontic procedures. The mean age for each group was 16 years. It was concluded that orthodontic treatment can be designed to : 1) counteract the forces which inhibit development of the maxillary alveolar process horizontally and vertically, 2) partially prevent the reduction in the forward growth of the maxilla, 3) provide adequate jaw and dental arch relationships, and 4) establish and maintain correct position of the maxillary segments.
实验和临床研究结果表明，腭裂患儿正常结构会出现不良适应性变化。据推测，这些与正常发育的偏差是可逆的，通过合理设计的治疗可以得到纠正或预防。在此基础上，针对本研究纳入的受试者数据，提出并检验了五个假设。受试者包括：1）16名无腭裂儿童；2）8名患有完全性单侧唇腭裂但未接受正畸治疗的儿童；3）16名患有完全性单侧唇腭裂且已接受上述正畸治疗的儿童。每组的平均年龄为16岁。研究得出结论，正畸治疗可以设计为：1）抵消水平和垂直方向抑制上颌牙槽突发育的力量；2）部分防止上颌向前生长的减少；3）提供足够的颌骨和牙弓关系；4）建立并维持上颌节段的正确位置。
