Brigham B A, Cooper I A, Wolf M M, Ding J C, Ironside P J
Aust N Z J Med. 1981 Jun;11(3):285-90.
Bone marrow necrosis occurred in two patients with non-Hodgkin's lymphoma. One had a four-year history of lymphoma for which he received combination chemotherapy. Severe bone pain, abdominal pain and fever occurred during the terminal part of his illness. The other patient presented initially with symptoms of bone pain and lymphadenopathy. At bone marrow examinations, both had anatomically extensive bone marrow necrosis with associated evidence of involvement by lymphoma. The previously recognized clinical features of bone marrow necrosis and its complications occurred in one or both of these illustrative cases, with the exception that bone tenderness was absent in both. Attempts were made to correlate the technetium-99m sulphur colloid scans with sites of disease as determined by the bone marrow examinations.
两名非霍奇金淋巴瘤患者发生了骨髓坏死。其中一名患者有四年淋巴瘤病史，接受过联合化疗。在疾病晚期出现了严重骨痛、腹痛和发热。另一名患者最初表现为骨痛和淋巴结病症状。骨髓检查时，两人均有解剖学上广泛的骨髓坏死，并伴有淋巴瘤累及的相关证据。在这两个典型病例中的一个或两个中出现了先前公认的骨髓坏死临床特征及其并发症，唯一的例外是两人均无骨压痛。尝试将锝-99m硫胶体扫描结果与骨髓检查确定的疾病部位进行关联。
