Lindemeyer R G, Baum R H, Hsu S C, Going R E
J Am Dent Assoc. 1981 Nov;103(5):719-22. doi: 10.14219/jada.archive.1981.0372.
Most pouch and plug chewing tobaccos with high sugar contents are able to support the growth of S mutans and S sanguis in vitro. Snuff and unprocessed tobacco, although not able to stimulate growth of these organisms, do not inhibit growth. Inhibitory agents present in tobacco leaves do not preclude use of tobacco sugars by the organisms tested. Because factors other than bacterial populations play an important role in caries initiation, clinical studies are needed to identify the effects of commercial tobacco on the human dentition.
大多数含糖量高的袋装和块状嚼烟在体外能够支持变形链球菌和 sanguis 链球菌的生长。鼻烟和未加工烟草虽然不能刺激这些微生物生长，但也不抑制其生长。烟叶中存在的抑制剂并不妨碍受试微生物利用烟草中的糖分。由于除细菌数量外的其他因素在龋齿发生过程中起重要作用，因此需要进行临床研究以确定商业烟草对人类牙列的影响。
