Ben-Aryeh H, Spielman A, Szargel R, Gutman D, Scharf J, Nahir M, Scharf Y
Oral Surg Oral Med Oral Pathol. 1981 Nov;52(5):487-90. doi: 10.1016/0030-4220(81)90359-5.
The flow rate and composition of whole unstimulated saliva were measured in fifteen healthy controls and in forty-eight xerostomic patients, fourteen suffering from xerostomia per se, twenty-two from xerostomia with keratoconjunctivitis sicca (KCS), and twelve from xerostomia, KCS, and rheumatoid arthritis. A significant lower salivary flow rate was found in all the xerostomic patients. Sodium, potassium, and IgA concentrations were significantly elevated in the KCS and in the RA + KCS group in comparison with the patients who had xerostomia per se and with the healthy controls. Sialochemistry is thus recommended for the diagnosis of Sjögren's syndrome in xerostomic patients.
对15名健康对照者以及48名口干症患者的全未刺激唾液流速和成分进行了测量。这48名患者中，14名仅患有口干症，22名患有伴有干燥性角结膜炎（KCS）的口干症，12名患有口干症、KCS和类风湿性关节炎。在所有口干症患者中均发现唾液流速显著降低。与仅患有口干症的患者及健康对照者相比，KCS组以及类风湿性关节炎 + KCS组中的钠、钾和IgA浓度显著升高。因此，推荐进行唾液化学分析以诊断口干症患者的干燥综合征。
