Taher A, Gilbert E, Shahidi N T
Am J Pediatr Hematol Oncol. 1981 Summer;3(2):121-5. doi: 10.1097/00043426-198100320-00002.
Erythroblastic islands are distinct anatomical units allowing direct transfer of ferritin molecule into developing erythroblasts. A patient with Fanconi's anemia who developed acute erythroleukemia and hypotransferrinemia exhibited numerous erythroblastic islands in the bone marrow. This unusual finding in our patient is thought to be in response to an increased demand for iron caused by neoplastic erythropoietic proliferation in the absence of an adequate amount of transferrin.
红细胞岛是独特的解剖学单位，可将铁蛋白分子直接转运至发育中的成红细胞。一名患有范科尼贫血并发展为急性红白血病和低转铁蛋白血症的患者，其骨髓中出现了大量红细胞岛。我们患者的这一异常发现被认为是对肿瘤性红细胞生成增殖在转铁蛋白量不足时导致的铁需求增加的一种反应。
