范科尼贫血：成红细胞的超微结构观察
Fanconi's anemia: ultrastructural observations on erythroblasts.
作者信息
Dell'Orbo C, Aricó M, Podestá A, Bianchi E
出版信息
Ultrastruct Pathol. 1983 Mar-Apr;4(2-3):145-50. doi: 10.3109/01913128309140785.
A case of Fanconi's anemia is reported. Particular attention was given to the ultrastructure of the erythroblasts. The main abnormalities are summarized as follows: (1) striking polymorphism of all the erythroblasts, (2) multiple nuclear cisternae showing several breaks, (3) admixture of nucleus and cytoplasm, (4) myelinic figures inside nuclear cisternae and cytoplasm, (5) moth-eaten nucleus, and (6) total absence of normal erythroblasts. These abnormalities were still visible after therapy in spite of clinical and hematologic improvement.
报告了1例范可尼贫血病例。对成红细胞的超微结构给予了特别关注。主要异常情况总结如下：(1)所有成红细胞均有明显的多形性；(2)多个核池出现多处断裂；(3)细胞核与细胞质混合；(4)核池和细胞质内有髓鞘样结构；(5)虫蚀状细胞核；(6)完全没有正常的成红细胞。尽管临床和血液学指标有所改善，但治疗后这些异常情况仍然可见。
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