碳水化合物特异性内吞作用：配体在溶酶体区室中的定位。

Haimes H B, Stockert R J, Morell A G, Novikoff A B

Proc Natl Acad Sci U S A. 1981 Nov;78(11):6936-9. doi: 10.1073/pnas.78.11.6936.

Carbohydrate-directed endocytosis is mediated by a receptor, the hepatic binding protein; it is responsible for the clearance of galactose-terminated glycoproteins from the circulation. This process was investigated by using lactosaminated ferritin which is recognized by this receptor. Ferritin was seen in elements of an extensive "lysosomal compartment" that includes secretory vacuoles, coated vesicles, and GERL. The compartment marked in hepatocytes by the distribution of ligand is similar to that previously described in Kupffer cells (marked by acid phosphatase reaction product and horseradish peroxidase reaction product).

碳水化合物导向的内吞作用由一种受体——肝结合蛋白介导；它负责从循环中清除半乳糖末端糖蛋白。通过使用被该受体识别的乳糖胺化铁蛋白对这一过程进行了研究。在一个广泛的“溶酶体区室”的成分中发现了铁蛋白，该区域包括分泌泡、被膜小泡和GERL。肝细胞中由配体分布所标记的区室与先前在库普弗细胞中描述的区室相似（由酸性磷酸酶反应产物和辣根过氧化物酶反应产物标记）。