人皮肤各组织中17β-羟基类固醇脱氢酶的活性

Activity of 17 beta-hydroxysteroid dehydrogenase in various tissues of human skin.

作者信息

Itami S, Takayasu S

出版信息

Br J Dermatol. 1981 Dec;105(6):693-9. doi: 10.1111/j.1365-2133.1981.tb00980.x.

DOI:10.1111/j.1365-2133.1981.tb00980.x

Abstract

The activity of 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) was assayed in various tissues microdissected from the freeze-dried human skin of fourteen subjects. The apocrine sweat gland, sebaceous gland and hair follicle possessed a high activity of 17 beta-HSD. The enzyme activity was negligible in the epidermis, except that the scalp epidermis showed much the same activity as the hair follicle. The demis showed variable activity because of contamination with other components.

摘要

在对14名受试者冻干人皮肤进行显微切割得到的各种组织中，测定了17β-羟类固醇脱氢酶（17β-HSD）的活性。顶泌汗腺、皮脂腺和毛囊具有较高的17β-HSD活性。除头皮表皮显示出与毛囊大致相同的活性外，表皮中的酶活性可忽略不计。由于受到其他成分的污染，真皮显示出不同的活性。