Kieny R, Eisenmann B, Jeanblanc B, Heitz A, Auad M, Kieny M T, Cinqualbre J
Thoraxchir Vask Chir. 1978 Aug;26(4):259-65. doi: 10.1055/s-0028-1096634.
45 pulmonary embolectomies have been carried out successfully, 10 by Trendelenburg's procedure, 35 with extracorporeal circulation. The latter method gives satisfactory results (34 survivals out of 36 attempts since 1970) and appears to be the procedure of choice. Any pulmonary trauma should be avoided at operation; embolectomy is done by intra-vascular suction. The hemodynamic status was always abnormal: 5 initial cardiac arrests, 20 cases of severe shock (9 demonstrating cardiac arrest on the operating table) and 11 cases with less severe shock. In 9 cases cyanosis, respiratory distress and signs of acute cor pulmonale were the clinical features of the massive embolus. In 9 patients the operation was performed after an unsuccessful trial of thrombolysis. Preoperative pulmonary angiography could be performed in 30 cases and always showed extensive pulmonary vascular obstruction of 60 to 95 per cent. These data are important for diagnosis and for assessment of the prognosis. Despite of present medical treatment with fibrinolytics, surgery is still advisable in the treatment of massive pulmonary embolism. The indications are moribund patients, those in whom thrombolysis is contraindicated or unsuccessful and those with massive pulmonary obstruction (greater than 60 per cent). In this latter subset thrombolytic therapy carries a high level of mortality.
已成功实施45例肺动脉栓子切除术,其中10例采用特伦德伦伯格式手术,35例采用体外循环。后一种方法取得了满意的效果(自1970年以来36次尝试中有34例存活),似乎是首选的手术方法。手术时应避免任何肺部创伤;栓子切除术通过血管内抽吸进行。血流动力学状态始终异常:5例最初出现心脏骤停,20例严重休克(9例在手术台上出现心脏骤停),11例休克程度较轻。9例患者出现发绀、呼吸窘迫和急性肺心病体征,为大块栓子的临床特征。9例患者在溶栓试验失败后接受了手术。30例患者术前行肺血管造影,均显示60%至95%的广泛肺血管阻塞。这些数据对诊断和预后评估很重要。尽管目前使用纤溶药物进行药物治疗,但在大块肺栓塞的治疗中手术仍然是可取的。适应证为濒死患者、溶栓治疗禁忌或失败的患者以及有大块肺阻塞(大于60%)的患者。在后一组患者中,溶栓治疗的死亡率很高。