72例寻常型银屑病患者的HLA-D分型：7种HLA-D等位基因的分布

HLA--D typing in 72 psoriasis vulgaris patients: distribution of seven HLA--D alleles.

作者信息

Grosse-Wilde H, Wüstner H, Albert E D, Kuntz B, Scholz S, Braun-Falco O

出版信息

Tissue Antigens. 1978 May;11(5):427-33. doi: 10.1111/j.1399-0039.1978.tb01279.x.

DOI:10.1111/j.1399-0039.1978.tb01279.x

Abstract

The phenotype distribution of seven HLA--D alleles among 72 unrelated Psoriasis vulgaris patients was investigated. Statistically significant deviation from the antigen frequency in healthy donors was found for a new HLA--D allele, locally designated EI, with a relative risk value of 5.97. This observation indicates that Psoriasis vulgaris belongs to the group of diseases with associations to HLA--B as well as HLA--D alleles.

摘要

对72例寻常型银屑病患者中7种HLA-D等位基因的表型分布进行了研究。发现一种新的HLA-D等位基因（当地命名为EI）的抗原频率与健康供者相比有统计学显著差异，相对风险值为5.97。这一观察结果表明，寻常型银屑病属于与HLA-B以及HLA-D等位基因相关的疾病组。