Keudell K, Powell G, Diemer R
Oral Surg Oral Med Oral Pathol. 1982 Feb;53(2):194-7. doi: 10.1016/0030-4220(82)90286-9.
The purpose of this investigation was to determine if anaerobic bacteria isolated from pulpal-periapical infections elicit a humoral immune response in the host. Results indicated that patients with pulp and periapical disease do not have significantly raised levels of IgG or IgM in their serum and that in the acute sera the precipitin antibody titer to the anaerobic bacteria was significantly higher in the patient group than in the control group. However, there was no significant difference in antibody titer for the convalescent sera in the patient and control groups or the acute and convalescent sera for the patient group.
本研究的目的是确定从牙髓根尖周感染中分离出的厌氧菌是否会在宿主体内引发体液免疫反应。结果表明，患有牙髓病和根尖周病的患者血清中IgG或IgM水平没有显著升高，并且在急性血清中，患者组针对厌氧菌的沉淀素抗体滴度显著高于对照组。然而，患者组和对照组的恢复期血清抗体滴度，以及患者组的急性血清和恢复期血清之间没有显著差异。
