Sack H, Röttinger E M, Rixen G
Strahlentherapie. 1978 Oct;154(10):663-7.
A retrospectively explored group consisting of 62 patients with lymphogranulomatosis Stage I to III, who had undergone primary radiation therapy, revealed recurrences in 23 cases (37%). (he recurrences are more frequent in unfavorable histological subclassifications and in advanced stages. 76% appear during the first two years, almost 90% of them in the region of lymphatic chains, preferably in the cervical or mediastinal region, in the hili and the contiguous lung. 75% of the recurrences are attributed to insufficient dosage. Typical recurrences, therefore, develop at the border of irradiation fields and are due to an incorrect calculation of the dose when applicating extended fields and individually shaped lead blocks. Other 25% are found in nonirradiated lymphatic areas.
对62例接受过原发性放射治疗的I至III期淋巴肉芽肿病患者进行回顾性研究，发现23例（37%）出现复发。复发在组织学亚分类不良和晚期更为常见。76%的复发发生在头两年内，其中近90%发生在淋巴链区域，最好是颈部或纵隔区域、肺门和相邻肺组织。75%的复发归因于剂量不足。因此，典型的复发发生在照射野边缘，是由于在应用扩大野和个体化铅挡块时剂量计算错误所致。另外25%的复发发生在未照射的淋巴区域。
