Teillet E, Delbrück H, Bayle-Weisgerber C, Andrieu J M, Asselain B, Dana M, Bernard J
Dtsch Med Wochenschr. 1979 Sep 28;104(39):1369-74. doi: 10.1055/s-0028-1129102.
A retrospective analysis on 482 patients with localised Hodgkin's disease revealed that none of those with primary high-cervical or primary infradiaphragmatic involvement had any infiltration of the mediastinum, either at the time or later. As a result, prophylactic mediastinal radiation was not practised if high-cervical or infradiaphragmatic lymph-nodes had been affected first. None of these patients had any mediastinal recurrence after at least seven years.