两例急性髓性白血病存在明显的核型异常。

Marked karyotype abnormalities in two cases of acute myelogenous leukemia.

作者信息

Sessarego M, Canepa L, Grammenu S, Scarrà G L, Ajmar F

出版信息

Cancer Genet Cytogenet. 1981 Dec;4(4):303-9. doi: 10.1016/0165-4608(81)90026-1.

Abstract

Two patients with acute myelogenous leukemia with severe chromosome abnormalities are described. The cytogenetic analysis shows the following karyotype: patient No. 1: 41,XY,-1,-2,-4,-5,-13,-15,-17,-18,-22,+5 markers; patient No. 2: 46,XY,-2,-5,-7,-13,+16,-21,-21,+5 markers. In each patient one set of double minute chromosomes was observed.

摘要

描述了两名患有严重染色体异常的急性髓性白血病患者。细胞遗传学分析显示以下核型：1号患者：41,XY,-1,-2,-4,-5,-13,-15,-17,-18,-22,+5个标记物；2号患者：46,XY,-2,-5,-7,-13,+16,-21,-21,+5个标记物。在每名患者中均观察到一组双微体染色体。