Mikhaĭlova G R, Rodova M A, Perekrest V V, Demidova S A, Zhdanov V M
Tsitologiia. 1978 Feb;20(2):232-5.
A comparative karyologic analysis of three continuous cell lines of different origin (HEp-2, FL and RH) has shown them differing from each other both in the number of chromosomes, and in marker chromosomes. In cultures HEp-2, the modal class consists of cells possessing 58-59 chromosomes, cells in cultures Fl and RH have 60 and 66 chromosomes, resp. Marker chromosomes both similar and not similar, i.e. characteristic of a given cell line only were found in all the investigated cell lines. The data obtained do not exclude a possibility of contamination of studied continuous cell cultires with HeLa cell line.
对三种不同来源的连续细胞系（HEp-2、FL和RH）进行的比较核型分析表明，它们在染色体数量和标记染色体方面均彼此不同。在HEp-2培养物中，众数类由具有58 - 59条染色体的细胞组成，Fl和RH培养物中的细胞分别有60条和66条染色体。在所有研究的细胞系中均发现了相似和不相似的标记染色体，即仅特定细胞系所特有的标记染色体。所获得的数据不排除所研究的连续细胞培养物被HeLa细胞系污染的可能性。
