用活性位点导向的17β-丙炔基取代孕激素类似物使人类胎盘17β-雌二醇脱氢酶和20α-羟基类固醇脱氢酶失活。 - Suppr | 超能文献

Inactivation of human placental 17 beta-estradiol dehydrogenase and 20 alpha-hydroxysteroid dehydrogenase with active site-directed 17 beta-propynyl-substituted progestin analogs.

作者信息

Tobias B, Covey D F, Strickler R C

出版信息

J Biol Chem. 1982 Mar 25;257(6):2783-6.

Abstract

摘要

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。

相似文献

1

Inactivation of human placental 17 beta-estradiol dehydrogenase and 20 alpha-hydroxysteroid dehydrogenase with active site-directed 17 beta-propynyl-substituted progestin analogs.用活性位点导向的17β-丙炔基取代孕激素类似物使人类胎盘17β-雌二醇脱氢酶和20α-羟基类固醇脱氢酶失活。

J Biol Chem. 1982 Mar 25;257(6):2783-6.

2

Human placental 17 beta-estradiol dehydrogenase and 20 alpha-hydroxysteroid dehydrogenase. Two activities at a single enzyme active site.人胎盘17β-雌二醇脱氢酶和20α-羟基类固醇脱氢酶。单一酶活性位点上的两种活性。

J Biol Chem. 1981 Jan 10;256(1):316-21.

3

Some kinetic properties of human placental estradiol-17 beta dehydrogenase: patterns of inhibition by adenine nucleotides.

Adv Enzyme Regul. 1978;17:363-71. doi: 10.1016/0065-2571(79)90022-0.

4

Human placental 17 beta-estradiol dehydrogenase and 20 alpha-hydroxysteroid dehydrogenase. Studies with 6 beta-bromoacetoxyprogesterone.人胎盘17β-雌二醇脱氢酶和20α-羟基类固醇脱氢酶。6β-溴乙酰氧基孕酮的研究。

J Biol Chem. 1983 Feb 10;258(3):1587-90.

5

17 beta-hydroxysteroid and 20 alpha-hydroxysteroid dehydrogenase activities of human placental microsomes: kinetic evidence for two enzymes differing in substrate specificity.

Arch Biochem Biophys. 1985 May 15;239(1):206-15. doi: 10.1016/0003-9861(85)90828-8.

6

Human placental estradiol 17 beta-dehydrogenase: evidence for inverted substrate orientation ("wrong-way" binding) at the active site.人胎盘雌二醇17β-脱氢酶：活性位点处底物反向取向（“错误方式”结合）的证据。

Biochemistry. 1988 Jun 14;27(12):4452-8. doi: 10.1021/bi00412a036.

7

Affinity labeling of arginyl residues at the catalytic region of estradiol 17 beta-dehydrogenase from human placenta by 16-oxoestrone.

Eur J Biochem. 1983 Jan 1;129(3):691-5. doi: 10.1111/j.1432-1033.1983.tb07104.x.

8

Identification of two histidyl residues in the active site of human placental estradiol 17 beta-dehydrogenase.人胎盘17β-雌二醇脱氢酶活性位点中两个组氨酸残基的鉴定。

Biochemistry. 1982 Jul 6;21(14):3322-6. doi: 10.1021/bi00257a012.

9

Periodate-oxidized NADP+ is a powerful inhibitor of human placental estradiol-17 beta dehydrogenase.

Biochem Biophys Res Commun. 1987 Jul 31;146(2):645-51. doi: 10.1016/0006-291x(87)90577-8.

10

Affinity labeling of human placental 17 beta-estradiol dehydrogenase and 20 alpha-hydroxysteroid dehydrogenase with 5'-[p-(fluorosulfonyl)benzoyl]adenosine.用5'-[对-(氟磺酰基)苯甲酰基]腺苷对人胎盘17β-雌二醇脱氢酶和20α-羟基类固醇脱氢酶进行亲和标记

Biochemistry. 1981 Sep 15;20(19):5546-9. doi: 10.1021/bi00522a030.

引用本文的文献

1

Oestradiol-17 alpha dehydrogenase from chicken liver.鸡肝中的雌二醇-17α脱氢酶。

Biochem J. 1984 Sep 15;222(3):761-8. doi: 10.1042/bj2220761.

2

Active-site directed inactivation of rat ovarian 20 alpha-hydroxysteroid dehydrogenase.大鼠卵巢20α-羟基类固醇脱氢酶的活性位点定向失活

Biochem J. 1986 Dec 15;240(3):717-23. doi: 10.1042/bj2400717.

3

Synthesis and evaluation of non-steroidal mechanism-based inactivators of 3 alpha-hydroxysteroid dehydrogenase.3α-羟基类固醇脱氢酶的非甾体类基于机制的失活剂的合成与评价

Biochem J. 1989 Aug 15;262(1):139-49. doi: 10.1042/bj2620139.