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[肿瘤细胞群体的多态性与选择过程。I. 艾氏-ICHPh腹水瘤株肿瘤细胞亚群]

[Polymorphism of a population of tumor cells and selective processes. I. Ehrlich-IChPh ascitic strain tumor cell subpopulation].

作者信息

Fomina M M, Minenkova E A, Poroshenko G G, Evseenko L S

出版信息

Tsitologiia. 1978 May;20(5):563-9.

PMID:694994
Abstract

4 types of marker chromosomes and of their combination in mouse ascite Ehrlich-I. Ch. Ph. tumor cells are described. Two most frequently encountered subpopulations of cells are found in the tumor: one--with A+B+2C and A+D+2D markers, and the other--with A1+A2+2B+D1+C markers. The former population dominated during 8 days, to be gradually substituted with the former subpopulation. Changes in the number of cells with certain chromosome number in the near-diploid and near-tetraploid cell zones were followed within one passage.

摘要

描述了小鼠腹水型艾氏-I.Ch.Ph.肿瘤细胞中4种标记染色体及其组合情况。在肿瘤中发现了两种最常见的细胞亚群:一种具有A + B + 2C和A + D + 2D标记,另一种具有A1 + A2 + 2B + D1 + C标记。前一种细胞亚群在8天内占主导地位,随后逐渐被后一种亚群取代。在一个传代过程中追踪了近二倍体和近四倍体细胞区中具有特定染色体数目的细胞数量变化。

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