北美鼠兔肌红蛋白：兔形目系统发育的评估
Ochotona princeps (pika) myoglobin: an appraisal of lagomorph phylogeny.
作者信息
Dene H, Goodman M, McKenna M C, Romero-Herrera A E
出版信息
Proc Natl Acad Sci U S A. 1982 Mar;79(6):1917-20. doi: 10.1073/pnas.79.6.1917.
Myoglobin was purified from skeletal muscle of the pika (Ochotona princeps) and its primary structure was determined. This sequence was added to the set of 64 already known vertebrate myoglobin sequences and used to evaluate the phylogenetic position of the pika among other mammals, using a computerized search procedure based on maximum parsimony criteria. The pika is clearly related to the rabbit (Oryctolagus cuniculus), with which it is traditionally associated as a member of the order Lagomorpha. A monophyletic group composed of Lagomorpha, Scandentia, and Carnivora is a consistent feature of the dendrograms produced. An association of Carnivora and Lagomorpha casts doubt on the results of those investigations using rabbit antisera in systematic studies and depending on carnivores as an outside reference group for cladogram construction.
从鼠兔（高原鼠兔）的骨骼肌中纯化出肌红蛋白，并确定了其一级结构。将该序列添加到已有的64种脊椎动物肌红蛋白序列中，并使用基于最大简约标准的计算机搜索程序，来评估鼠兔在其他哺乳动物中的系统发育位置。鼠兔显然与兔子（穴兔）有关，传统上它作为兔形目成员与兔子联系在一起。由兔形目、树鼩目和食肉目组成的单系群是所产生的系统树图的一个一致特征。食肉目和兔形目的关联对那些在系统研究中使用兔抗血清并依靠食肉动物作为构建分支图的外部参考组的研究结果提出了质疑。
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