Hanis N M, Holmes T M, Newill V A, Smith F R, Smith L G
Ann N Y Acad Sci. 1982;381:83-90. doi: 10.1111/j.1749-6632.1982.tb50370.x.
A cohort study covering the eight year period, 1970-1977, identified eight deaths attributed to brain cancer among employees at a refinery/chemical plant. Five of the cases were primary brain cancers and three were either metastatic from another site or the site was undetermined. A ninth case of brain tumor unspecified was identified. Five primary brain cancers would have been expected, based on national statistics. Some issues and dilemmas related to such a cohort study were discussed.