Kuo M C
J Forensic Sci. 1982 Apr;27(2):438-44.
The use of the principles of genetic inheritance to link a bloodstain to a missing victim is discussed. Genetic marker typing can determine whether the parents of the missing victim are possible parents of the bloodstain source. Given a parental inclusion, it is possible to calculate the probability that a randomly selected couple would possess the necessary genetic combinations to be the parents of the person who bled. The applications of this concept using several genetic marker systems are examined. General formulas have been developed for the probability calculation using phenotype distribution frequencies and gene frequencies. This approach was applied to a homicide case in which it was shown that the victim's parents were among only 0.8% of couples from the general population who would be able to bequeath the genetic marker types found in the bloodstain. This evidence was helpful in producing a conviction of first degree murder.
本文讨论了利用遗传继承原理将血迹与失踪受害者联系起来的方法。基因标记分型可以确定失踪受害者的父母是否可能是血迹来源者的父母。如果确定父母与血迹匹配，就可以计算出随机选择的一对夫妇拥有成为出血者父母所需基因组合的概率。本文研究了使用几种基因标记系统的这一概念的应用。已经开发出了使用表型分布频率和基因频率进行概率计算的通用公式。这种方法被应用于一起凶杀案，结果表明，在普通人群中，只有0.8%的夫妇能够遗传出血迹中发现的基因标记类型，而受害者的父母就在其中。这一证据有助于判定一级谋杀罪。
