• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Hypothetical mechanism of therapeutic synergism induced by the combination of 6-thioguanine and 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride.

作者信息

Fujimoto S, Ogawa M, Sakurai Y

出版信息

Cancer Res. 1982 Oct;42(10):4079-85.

PMID:6955008
Abstract
摘要

相似文献

1
Hypothetical mechanism of therapeutic synergism induced by the combination of 6-thioguanine and 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride.
Cancer Res. 1982 Oct;42(10):4079-85.
2
Potentiation of therapeutic effects of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride by 6-thioguanine in mouse tumor systems: comparison with other antimetabolites.
Gan. 1980 Feb;71(1):60-72.
3
Therapeutic synergism elicited by the combination of 6-thioguanine and 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride: synergistic cytocidal activity against L1210 cells in vitro.
Gan. 1980 Oct;71(5):659-66.
4
Combination chemotherapy of 6-thioguanine with various antitumor agents against murine leukemia L-1210.
Gan. 1977 Oct;68(5):543-52.
5
Ultrastructral changes induced by 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea in L1210 lymphocytic leukemia cells in mice.3-[(4-氨基-2-甲基-5-嘧啶基)甲基]-1-(2-氯乙基)-1-亚硝基脲诱导小鼠L1210淋巴细胞白血病细胞的超微结构变化
Cancer Res. 1980 Jan;40(1):133-8.
6
Lethal toxicity and myelotoxicity to mice of the combination of 6-thioguanine and 3-[(4-amine-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride.
Gan. 1980 Oct;71(5):667-73.
7
Effect of 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride on experimental brain tumors.盐酸1-(4-氨基-2-甲基-5-嘧啶基)甲基-3-(2-氯乙基)-3-亚硝基脲对实验性脑肿瘤的作用
Cancer Res. 1979 Jul;39(7 Pt 1):2687-90.
8
Combination therapy: some concepts and results.
Cancer Chemother Rep 2. 1974 Mar;4(1):137-45.
9
Effect of 1-(2-chloroethyl)-3-isobutyl-3-(beta-maltosyl)-1-nitrosourea on experimental tumors.1-(2-氯乙基)-3-异丁基-3-(β-麦芽糖基)-1-亚硝基脲对实验性肿瘤的作用
Gan. 1982 Jun;73(3):480-7.
10
Potentiation by squalene of antitumor effect of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-nitros ourea in a murine tumor system.在小鼠肿瘤系统中，角鲨烯对3-[(4-氨基-2-甲基-5-嘧啶基)甲基]-1-(2-氯乙基)-亚硝基脲抗肿瘤作用的增强作用。
Jpn J Cancer Res. 1985 Oct;76(10):1021-6.

引用本文的文献

1
Treatment of pediatric low-grade gliomas with a nitrosourea-based multiagent chemotherapy regimen.采用基于亚硝基脲的多药化疗方案治疗儿童低级别胶质瘤。
J Neurooncol. 1997 May;32(3):235-41. doi: 10.1023/a:1005736104205.
2
Phase I study of BCNU and intravenous 6-mercaptopurine in patients with anaplastic gliomas.卡氮芥与静脉注射6-巯基嘌呤用于间变性胶质瘤患者的I期研究。
Cancer Chemother Pharmacol. 1992;30(4):272-6. doi: 10.1007/BF00686294.