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人松果体中5-甲氧基吲哚的浓度。

Concentration of 5-methoxyindoles in the human pineal gland.

作者信息

Beck O, Borg S, Lundman A

出版信息

J Neural Transm. 1982;54(1-2):111-6. doi: 10.1007/BF01249284.

DOI:10.1007/BF01249284
PMID:6955450
Abstract

The pineal gland concentration of the four 5-methoxyindoles: melatonin, 5-methoxytryptamine, 5-methoxytryptophol and 5-methoxyindole-3-acetic acid, were measured by gas chromatography-mass spectrometry. The pineal glands were obtained from 11 subjects 2-3 hours post mortem. The concentration of 5-methoxytryptophol ranged from 4-93 pmoles/g, 5-methoxyindole-3-acetic acid from 79-560 pmoles/g and melatonin from 24-6860 pmoles/g. 5-methoxytryptamine was present only in trace amounts (0-12 pmoles/g). A variation over time of these compounds was not evident from the data obtained.

摘要

采用气相色谱-质谱联用仪测定了褪黑素、5-甲氧基色胺、5-甲氧基色醇和5-甲氧基吲哚-3-乙酸这四种5-甲氧基吲哚在松果体中的浓度。松果体取自11名受试者死后2至3小时的样本。5-甲氧基色醇的浓度范围为4至93皮摩尔/克,5-甲氧基吲哚-3-乙酸为79至560皮摩尔/克,褪黑素为24至6860皮摩尔/克。5-甲氧基色胺仅以痕量存在(0至12皮摩尔/克)。从所获数据中未明显看出这些化合物随时间的变化情况。

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本文引用的文献

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Melatonin content of the human pineal gland.人类松果体的褪黑素含量。
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2
5-Methoxyindoles in pineal gland of cow, pig, sheep and rat.牛、猪、羊和大鼠松果体中的5-甲氧基吲哚。
Naunyn Schmiedebergs Arch Pharmacol. 1981 Dec;318(1):49-55. doi: 10.1007/BF00503312.
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