Raynaud F, Pévet P
CNRS URA 1332, Université Louis Pasteur, Strasbourg, France.
J Pineal Res. 1991 Aug;11(1):7-11. doi: 10.1111/j.1600-079x.1991.tb00820.x.
This work investigates the rhythmic synthesis of pineal 5-methoxytryptamine and related indoles in golden hamsters as a function of ambient temperature. 5-methoxytryptamine, 5-methoxytryptophol, 5-methoxyindole acetic acid, and melatonin were measured by high pressure liquid chromatography (HPLC) in the pineal gland of golden hamsters after inhibition of monoamine oxidase. In our experimental conditions, the pineal 5-methoxyindole concentrations of hamsters kept at 5 degrees C were similar to those observed at 20 degrees C. These results suggest that low temperature, which is known to accelerate the short photoperiod-induced gonadal regression, acts at a level different to that of the pineal gland or affects another compound in the pineal gland.
本研究调查了金黄仓鼠松果体中5-甲氧基色胺及相关吲哚的节律性合成与环境温度的关系。在抑制单胺氧化酶后，通过高压液相色谱法（HPLC）测定了金黄仓鼠松果体中的5-甲氧基色胺、5-甲氧基色醇、5-甲氧基吲哚乙酸和褪黑素。在我们的实验条件下，饲养在5摄氏度的仓鼠松果体中5-甲氧基吲哚的浓度与在20摄氏度时观察到的浓度相似。这些结果表明，已知能加速短光照周期诱导的性腺退化的低温，其作用水平与松果体不同，或者影响松果体中的另一种化合物。
