Güllner H G
Prostaglandins Leukot Med. 1982 Jun;8(6):545-51.
The urinary excretion of free dopamine was measured in patients with increased prostaglandin synthesis and the effect of inhibition of prostaglandin synthesis on dopamine excretion was examined. Dopamine excretion in patients with Bartter's syndrome was not different from that of normal controls. Treatment with indomethacin for 6 or 7 days did not affect dopamine excretion in either Bartter's syndrome or in a group of normal control subjects. It appears that changes in endogenous prostaglandin synthesis do not affect urinary dopamine excretion.
在前列腺素合成增加的患者中测量了游离多巴胺的尿排泄量，并研究了抑制前列腺素合成对多巴胺排泄的影响。巴特综合征患者的多巴胺排泄量与正常对照组无异。用吲哚美辛治疗6或7天对巴特综合征患者或一组正常对照受试者的多巴胺排泄均无影响。看来内源性前列腺素合成的变化不影响尿多巴胺排泄。
