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抽动秽语综合征的流行病学:一项初步研究。

The epidemiology of Tourette's syndrome: a pilot study.

作者信息

Jagger J, Prusoff B A, Cohen D J, Kidd K K, Carbonari C M, John K

出版信息

Schizophr Bull. 1982;8(2):267-78. doi: 10.1093/schbul/8.2.267.

Abstract

A new, precoded, self-report questionnaire was used to collect information on 75 patient members of the Tourette Syndrome Association. This diverse group of Tourette's syndrome (TS) patients supplied by mail detailed medical, symptom, developmental, family, and personal history information. Analysis of these data supported the usefulness and validity of the questionnaire, and also indicated that the diagnosis of TS is being made earlier; attentional difficulties may be basic to the disorder; haloperidol is an effective treatment for many patients, but alternative treatments are needed because unpleasant side effects of haloperidol often lead to discontinued use, and TS is disabling for many with most patients reporting serious problems in one or more areas of functioning.

摘要

一份新的、预先编码的自我报告问卷被用于收集抽动秽语综合征协会75名患者成员的信息。这群多样化的抽动秽语综合征(TS)患者通过邮件提供了详细的医疗、症状、发育、家庭和个人病史信息。对这些数据的分析支持了该问卷的实用性和有效性,还表明TS的诊断正在提前进行;注意力障碍可能是该疾病的基础;氟哌啶醇对许多患者是一种有效的治疗方法,但由于氟哌啶醇令人不适的副作用常常导致停药,所以需要其他替代治疗方法,而且TS使许多患者致残,大多数患者报告在一个或多个功能领域存在严重问题。

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