Kulkarni R, Murray D L, Gupta S, de Mendonca W C, Leader I
Am J Pediatr Hematol Oncol. 1982 Summer;4(2):141-5.
A case of multiple splenic aspergillomas (mycetomas) without systemic involvement is a patient with acute lymphoblastic leukemia is described. The patient underwent splenectomy without concomitant antifungal therapy. There has been no recurrence of the disease for over two years. Granulocytopenia and airborn contamination may have played a role in the acquisition of this disease. The value of serology, radionuclide scans and cultures in the diagnosis of Aspergillus infections is explored. The role of granulocyte transfusions, antifungal chemotherapy and the achievement of bone marrow remission in localization of the fungal disease is discussed.
本文描述了一例患急性淋巴细胞白血病且无全身感染的多发性脾脏曲菌肿（霉菌瘤）患者。该患者接受了脾切除术，未同时进行抗真菌治疗。疾病已两年多未复发。粒细胞减少和空气传播污染可能在该疾病的发生中起了作用。探讨了血清学、放射性核素扫描及培养在曲霉菌感染诊断中的价值。讨论了粒细胞输注、抗真菌化疗及骨髓缓解在真菌病定位中的作用。
