Knapp E, Abbrederis K, Braunsteiner H
Wien Klin Wochenschr. 1978 Sep 1;90(16):603-11.
Out of 1800 patients examined for valvular heart disease, 19 were found to have the mitral valve prolapse syndrome (MVPS). The relevant literature is reviewed and the epidemiology and aetiology of the disease are discussed. 50% of the patients had a history of endomyocarditis. The special diagnostic value of echocardiography is emphasized. Sudden death (observed in 2 young patients) and the grave complication of bacterial endocarditis (observed in 3 patients and usually caused by Streptococcus viridans) can occur in this condition. Prophylactic therapy with beta-blocking drugs and antibiotics seems warranted. The case history of one patient with MVPS under observation for eight years, who developed bacterial endocarditis from a dental focus is reported in greater detail as a typical case.
在1800名接受瓣膜性心脏病检查的患者中，发现19人患有二尖瓣脱垂综合征（MVPS）。本文回顾了相关文献，并讨论了该疾病的流行病学和病因。50%的患者有心肌内膜炎病史。强调了超声心动图的特殊诊断价值。这种情况下可能会发生猝死（在2名年轻患者中观察到）和细菌性心内膜炎的严重并发症（在3名患者中观察到，通常由草绿色链球菌引起）。使用β受体阻滞剂和抗生素进行预防性治疗似乎是必要的。作为典型病例，更详细地报告了一名观察八年的MVPS患者的病史，该患者因牙源性病灶引发了细菌性心内膜炎。
