[Histoenzymological characteristics of the adrenal cortical reaction in variants of experimental pancreatitis].

In the early stages of experiments there was a structural-metabolic reconstruction in the adrenal cortex, manifest by changes in interzonal relations and dissociation of the activity of enzymes responsible for energy supply and synthesis of steroid hormones. Analogous changes were also seen later on. However, in the early stages that process was a response to the pancreas injury, whereas in the later period it preceded the emergence of repeated lesions in the gland. In animals with experimental pancreatitis, administration of metapyrone caused an activation of NAD-diaphorase in the glomerular and reticular zones and concurrent potentiation of the activity of glucose-6-phosphate dehydrogenase in all 3 zones of the adrenal cortex.