Prochukhanov R A, Rostovtseva T I
Biull Eksp Biol Med. 1977 Nov;84(11):606-9.
A method of quantitative histenzymatic analysis was applied for determination of the involution changes of the neuroendocrine system. The activity of NAD- and NADP-reductases, acid and alkaline phosphatases, glucose-6-phosphoric dehydrogenase, 3-OH-steroid-dehydrogenase, 11-hydroxysteroid dehydrogenases was investigated in the adenohypophysis and in the adrenal cortex of rats aged 4 and 12 months. There were revealed peculiarities attending the structural-metabolic provision of physiological reconstructions of the neuro-endocrine system under conditions of the estral cycle at the early involution stages. An initial reduction of the cell ular-vascular transport with the retention of the functional activity of the intracellular organoids was demonstrated in ageing animals.
采用定量组织酶分析方法来测定神经内分泌系统的 involution 变化。研究了 4 个月和 12 个月龄大鼠腺垂体和肾上腺皮质中 NAD - 和 NADP - 还原酶、酸性和碱性磷酸酶、葡萄糖 - 6 - 磷酸脱氢酶、3 - OH - 类固醇脱氢酶、11 - 羟基类固醇脱氢酶的活性。揭示了在早期 involution 阶段发情周期条件下神经内分泌系统生理重建的结构 - 代谢供应的特殊性。在衰老动物中证实了细胞 - 血管运输最初减少,而细胞内细胞器的功能活性得以保留。