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反思:伦理与重组DNA辩论

Reflections: ethics and the recombinant DNA debate.

作者信息

Robb J W

出版信息

J Craniofac Genet Dev Biol. 1982;2(1):51-63.

PMID:6957414
Abstract

This essay is an attempt to apply a mode of ethical reflection to questions related to the recombinant DNA debate. The author suggests that adequate ethical analysis must include at least five aspects of a moral situation 1) the nature of the act itself; 2) consequences that result from an action or decision; 3) civil and criminal laws; 4) moral principles; and 5) motivation or intention. This paradigm for analysis is applied to the recombinant DNA scene, particularly as these factors relate to 1) risks vs benefits; 2) laws and regulations; 3) the marketplace; and 4) human genetic intervention. The analysis does not provide answers to these vexing questions, but attempts to raise the consciousness level of the reader concerning significant ethical issues. Undergirding the discussion is the humanistic theme of the primacy of the concern for the public good, and that freedom of inquiry can only survive in a socially conscious context. Fear of the unknown is no reason for prohibiting DNA research, but since the stakes are high as new developments emerge that pertain to the genetic restructuring of the human species, the author suggests that caution and responsible judgment are mandatory. Since ethics is concerned with ideal moral judgments, and applied ethics relates to the real world in which we function, the demand for clear and careful thought concerning the short-term and long-term consequences of our work is a primary ingredient of what it means to be responsible. In the final analysis, ethical responsibility rests on the individual; without a sense of personal integrity and what that implies about oneself and society, blatant opportunism can easily become the generally accepted mode of behavior and decision. If this occurs, traditional ethical concerns become irrelevant.

摘要

本文试图将一种伦理反思模式应用于与重组DNA辩论相关的问题。作者认为,充分的伦理分析必须至少包括道德情境的五个方面:1)行为本身的性质;2)行动或决策产生的后果;3)民法和刑法;4)道德原则;5)动机或意图。这种分析范式被应用于重组DNA领域,特别是当这些因素与以下方面相关时:1)风险与收益;2)法律法规;3)市场;4)人类基因干预。该分析并未为这些棘手问题提供答案,而是试图提高读者对重大伦理问题的认识水平。讨论的基础是人文主义主题,即关注公共利益的首要性,以及探究自由只有在具有社会意识的背景下才能存续。对未知的恐惧并非禁止DNA研究的理由,但由于随着与人类物种基因重组相关的新进展不断出现, stakes(此处可能有误,可根据上下文修正为“风险”之类的准确含义)很高,作者建议谨慎和负责任的判断是必不可少的。由于伦理学关注理想的道德判断,而应用伦理学涉及我们实际生活的现实世界,对我们工作的短期和长期后果进行清晰而审慎的思考的要求,是负责任的含义的一个主要要素。归根结底,伦理责任在于个人;没有个人诚信意识以及这种意识对自己和社会的意义,公然的机会主义很容易成为普遍接受的行为和决策模式。如果这种情况发生,传统的伦理关切就会变得无关紧要。

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