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二极管激光治疗抗凝治疗老年患者颊黏膜纤维脂肪瘤:病例报告与文献综述

Diode Laser Treatment for Buccal Mucosa Fibrolipoma in an Elderly Patient on Anticoagulants: Case Report and Literature Review.

作者信息

Pellegrini Matteo, Ghizzoni Martina, Pulicari Federica, Kuhn Elisabetta, Scribante Andrea, Spadari Francesco

机构信息

Maxillofacial Surgery and Dental Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.

Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.

出版信息

Case Rep Dent. 2025 Aug 8;2025:8847648. doi: 10.1155/crid/8847648. eCollection 2025.

DOI:10.1155/crid/8847648
PMID:40822912
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12356663/
Abstract

Lipomas are benign neoplasms originating from mesenchymal soft tissue, primarily composed of mature adipocytes and surrounded by a fibrous capsule. While they are relatively common in the head and neck region, oral cavity involvement is rare. Fibrolipoma (FL) is a variant characterized by lobules of adipocytes with dense collagen bands. Its etiology remains uncertain and can occasionally be found in the buccal mucosa. Surgical excision is the gold standard for oral lipomas, and the prognosis is generally favorable. This case report describes the excision of a buccal mucosa FL in a 92-year-old patient undergoing anticoagulant therapy using a diode laser. A 92-year-old patient with a medical history of benign prostatic hyperplasia and hypertension, under anticoagulant therapy, presented with a painless buccal mucosa swelling. The growth affected both the superficial and submucosal layers. Surgical removal of the FL using a diode laser was performed. The diode laser excision of the FL was carried out successfully, with immediate cauterization, eliminating the need for sutures or hemostatic agents. Histopathological examination confirmed the diagnosis of FL. Postoperative healing was uneventful at both 1- and 3-month follow-ups. Oral FLs are rare benign tumors primarily treated through surgical excision. In this case, the use of a diode laser provided effective hemostasis, minimal scarring, and rapid recovery, making it a suitable option for patients under anticoagulant therapy. While this report presents promising results, further cases with longer follow-up periods are needed to establish the effectiveness and safety of this technique. Laser technology continues to emerge as a valuable tool in oral pathology and surgery, offering minimally invasive alternatives to traditional approaches.

摘要

脂肪瘤是起源于间叶软组织的良性肿瘤,主要由成熟脂肪细胞组成,并被纤维包膜包裹。虽然它们在头颈部区域相对常见,但口腔受累情况罕见。纤维脂肪瘤(FL)是一种以脂肪细胞小叶伴有致密胶原带为特征的变体。其病因尚不确定,偶尔可在颊黏膜发现。手术切除是口腔脂肪瘤的金标准,预后通常良好。本病例报告描述了一名92岁接受抗凝治疗的患者使用二极管激光切除颊黏膜纤维脂肪瘤的过程。一名有良性前列腺增生和高血压病史且正在接受抗凝治疗的92岁患者,出现无痛性颊黏膜肿胀。病变累及表层和黏膜下层。使用二极管激光对纤维脂肪瘤进行了手术切除。成功实施了纤维脂肪瘤的二极管激光切除,术中立即止血,无需缝合或使用止血剂。组织病理学检查确诊为纤维脂肪瘤。术后1个月和3个月随访时愈合情况良好。口腔纤维脂肪瘤是罕见的良性肿瘤,主要通过手术切除治疗。在本病例中,使用二极管激光实现了有效的止血、最小的瘢痕形成和快速恢复,使其成为接受抗凝治疗患者的合适选择。虽然本报告呈现了有前景的结果,但需要更多随访期更长的病例来确定该技术的有效性和安全性。激光技术在口腔病理学和手术中持续成为一种有价值的工具,为传统方法提供了微创替代方案。

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Fibrolipoma of the Buccal Mucosa in a Geriatric Patient.
老年患者颊黏膜纤维脂肪瘤
J Microsc Ultrastruct. 2022 Aug 4;10(4):204-207. doi: 10.4103/jmau.jmau_97_21. eCollection 2022 Oct-Dec.
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Management of Aberrant Frenal Attachments in Adults by Scalpel Method and 980 nm Diode Laser.采用手术刀法和980纳米二极管激光治疗成人异常系带附着
Case Rep Dent. 2023 Jan 4;2023:7258637. doi: 10.1155/2023/7258637. eCollection 2023.
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Rare fibrolipoma of attached gingiva: A case report and review of the literature.附着龈罕见纤维脂肪瘤:一例报告并文献复习
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