Ehrig E, Schott G
Zentralbl Gynakol. 1982;104(13):769-76.
Reported in the paper is continuous extra-amniotic application of Prostaglandin F2 alpha (PG F2 alpha) to 70 juvenile primigravidae for termination of pregnancy. Successful priming was achieved in 54 patients after three and a half hours of induction, following administration of an average induction dose of 3 mg PG F2 alpha. Induced abortion was "incomplete or retained" and, therefore, stopped in 16 cases. An account is given of advantages of the above approach over intermittent intra-uterine application. The technique described in this paper was found to be suitable and commendable for minimizing of side-effects and risk as well as for better and individual controllability. It has also proved to reduce the variety of contra-indications to prostaglandin induction for patients with pre-existing diseases. Continuous intracavitary induction of labour may be considered as a justified alternative to the risks implied in other techniques of interruption.
该论文报道了对70例初产未成年孕妇持续进行羊膜外前列腺素F2α(PG F2α)给药以终止妊娠的情况。在平均诱导剂量为3毫克PG F2α给药后,经过三个半小时的诱导,54例患者成功启动。16例患者因诱导流产“不完全或有残留”而终止。阐述了上述方法相对于间歇性宫内给药的优势。本文所述技术被发现适合且值得称赞,可将副作用和风险降至最低,实现更好的个体化可控性。它还被证明可减少患有基础疾病患者使用前列腺素诱导的各种禁忌症。持续腔内引产可被视为其他终止妊娠技术所涉风险的合理替代方法。