[Immunogenic properties of cholerogen-toxoid and killed corpuscular vaccine in acute experiments on guinea pigs].

A comparative assessment of the immunogenicity of cholerogen toxoid and of killed corpuscular cholera vaccine was given. Guinea pigs immunized with cholerogen toxoid acquired a greater resistance to the intrapulmonary infection with virulent cholera vibrio culture (immunity index--2.1.10(4)) than those immunized with killed corpuscular vaccine (immunity index--3.5.10(2)). Immunogenicity of cholerogen toxoid could be increased in its combined administration with killed corpuscular vaccine.