Jouppila R, Jouppila P, Koivisto M, Virkkunen L, von Wendt L, Pakarinen A
Acta Anaesthesiol Scand. 1978;22(5):491-6. doi: 10.1111/j.1399-6576.1978.tb01328.x.
Maternal, cord and neonatal blood creatine-phosphokinase (CK) activities and CK-isoenzymes were determined in connection with 24 labours after normal pregnancies. In eight cases there was a normal vaginal delivery; in another eight cases there was a normal vaginal delivery with segmental epidural analgesia; and in the remaining eight cases there was an elective caesarean section under general anaesthesia. The lowest maternal blood CK-activities were seen in connection with caesarean section. There was a statistically significant difference in the maternal CK levels after delivery between cases with caesarean section and normal labour (P less than 0.05) and between cases with caesarean section and labour with segmental epidural analgesia (P less than 0.001). Most of the maternal CK-activity was of muscular type, and there were no statistically significant differences in isoenzyme fractions between the different groups. The neonatal blood CK-activities were at their peak at the age of 1 day in all groups. Between the groups there were no statistically significant differences in cord or neonatal blood CK-activities at any time. Most of the cord and neonatal blood CK-activity was also of muscular type, and there were no significant differences in the CK-isoenzyme fractions between the groups.
对24例正常妊娠后的分娩过程测定了母体、脐带血和新生儿血中的肌酸磷酸激酶（CK）活性及CK同工酶。其中8例为正常阴道分娩；另外8例为正常阴道分娩并采用节段性硬膜外镇痛；其余8例为择期剖宫产全麻。剖宫产时母体血CK活性最低。剖宫产病例与正常分娩病例产后母体CK水平存在统计学显著差异（P<0.05），剖宫产病例与采用节段性硬膜外镇痛分娩病例产后母体CK水平存在统计学极显著差异（P<0.001）。母体大部分CK活性为肌肉型，不同组间同工酶组分无统计学显著差异。所有组新生儿血CK活性在出生1天时达到峰值。各组间在任何时间点脐带血或新生儿血CK活性均无统计学显著差异。脐带血和新生儿血中大部分CK活性也为肌肉型，各组间CK同工酶组分无显著差异。
