Loeb C, Priano A, Albano C
Acta Neurol Scand. 1978 Jun;57(6):471-80. doi: 10.1111/j.1600-0404.1978.tb02850.x.
The clinical features of 102 cases with transient attacks due to cerebral ischemia were evaluated, and 94 out of 102 cases were followed for an average of 6 years. 1) The clinical study makes comparisons between two groups of patients grouped under the somewhat new definition of Reversible Ischemic Attacks (RIA): classical Transient Ischemic Attacks (TIA) and Stroke with Full Recovery (SFR), in which a complete recovery took place over a longer period, on the average 3 weeks. 2) SFR constitutes the 34.31% of the total cases with transient ischemic episodes. In the carotid district the onset was more frequently gradual in SFR than in TIA and aphasia more frequent in TIA than in SFR. Multiple attacks prevailed in TIA over the SFR group. The definition of transient attack due to ischemia is discussed. 3) Completed strokes occurred in 11 cases (11.7%) with RIA. Hypertension and cardiac disease were significantly frequent in cases with subsequent stroke. The conclusion was reached that TIA is a symptom, not a pathological state, and TIA should be considered an important symptom but not a specific harbinger of completed stroke.
对102例脑缺血性短暂发作患者的临床特征进行了评估，其中102例中的94例平均随访了6年。1）临床研究对两组根据可逆性缺血发作（RIA）这一相对新的定义分组的患者进行了比较：经典短暂性脑缺血发作（TIA）和完全恢复性卒中（SFR），后者平均在较长时间内，即平均3周实现了完全恢复。2）SFR占短暂性缺血发作总病例数的34.31%。在颈动脉区，SFR的起病较TIA更常呈渐进性，TIA的失语症较SFR更常见。TIA的多次发作比SFR组更为普遍。讨论了缺血性短暂发作的定义。3）11例（11.7%）RIA患者发生了完全性卒中。高血压和心脏病在随后发生卒中的病例中显著常见。得出的结论是，TIA是一种症状，而非病理状态，TIA应被视为一个重要症状，但并非完全性卒中的特异性先兆。
