Deffez J P, Artaud C, Franchi-Deffez I, Pillion G
Rev Stomatol Chir Maxillofac. 1982;83(6):360-6.
Children with terminal renal failure require iterative dialysis while awaiting kidney graft, and these have to be repeated over a period of years until a suitable graft presenting histocompatibility with the receiver is found. This has a considerable growth retardation effect (-3 to -6 SD, according to the age at onset of terminal failure). Two features appear to be paradoxical in these children. 1) In spite of a high carbohydrate diet and generally poor oral hygiene, they present a low prevalence of caries, probably related to modified salivary components. The only objective finding is an increase in salivary urea levels. 2) In spite of harmonious hypotrophy, no particular encumbrance of the dental arch is observed. Alveolar growth, contemporary with dental eruption, is sufficient to compensate possible hypotrophy of maxillary bone bases.
终末期肾衰竭患儿在等待肾移植期间需要反复进行透析，且这些透析必须在数年时间内反复进行，直到找到与受体具有组织相容性的合适移植物。这具有相当大的生长迟缓效应（根据终末期肾衰竭发病时的年龄，为-3至-6标准差）。这些儿童有两个看似矛盾的特征。1）尽管碳水化合物饮食量高且口腔卫生普遍较差，但他们的龋齿患病率较低，这可能与唾液成分改变有关。唯一的客观发现是唾液尿素水平升高。2）尽管存在协调性发育不良，但未观察到牙弓有特别的压迫情况。与牙齿萌出同时发生的牙槽生长足以补偿上颌骨基部可能出现的发育不良。
