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[急性白血病患儿的肺部病变]

[Lesions of the lungs in children with acute leukemia].

作者信息

Vasil'ev A V

出版信息

Arkh Patol. 1982;44(12):41-8.

PMID:6962689
Abstract

Investigation of the lungs of 65 children who died of acute leukemia, revealed pathological alterations in 39 of them. Specific leukemic infiltration of the lung parenchyma was found in 29.3%, but it did not play an important role in tanathogenesis. Pneumonias were diagnosed in 46.1% of the observations being the main cause of death in 23%. The inflammatory processes showed a marked tendency for spread because of low immunologic responsiveness of the patients and poor neutrophil reaction. Because of this, segmental pneumonias predominated in our observations, and in 5 cases total bilateral interstitial pneumonias had developed. Three of them were due to Pneumocystis carinii and two were drug pulmonitis.

摘要

对65名死于急性白血病的儿童的肺部进行调查发现,其中39名有病理改变。肺实质的特异性白血病浸润见于29.3%的病例,但在致死原因中不起重要作用。46.1%的观察病例诊断为肺炎,其中23%是主要死因。由于患者免疫反应低下和中性粒细胞反应差,炎症过程有明显的扩散倾向。因此,在我们的观察中节段性肺炎占主导,5例发展为双侧全间质肺炎。其中3例由卡氏肺孢子虫引起,2例为药物性肺炎。

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