Grubaugh W, Sharp D C, Berglund L A, McDowell K J, Kilmer D M, Peck L S, Seamans K W
J Reprod Fertil Suppl. 1982;32:293-5.
When mares were pinealectomized in summer or in winter there was no difference in the annual ovulation date of these animals and of pineal-intact controls during the first post-operative breeding season but in the second season the ovulation date of the winter pinealectomized mares was significantly delayed, suggesting a long-term but clear pineal involvement in seasonal reproductive patterns. Exposure of pinealectomized mares to a stimulatory photoperiod failed to advance the average date of first annual ovulation and was similar to that of intact mares receiving no stimulatory lighting. The results indicate that pinealectomy blocks the ability to respond to photostimulation. In intact mares plasma melatonin concentrations were significantly increased during darkness (P less than 0 . 003) but pinealectomized mares demonstrated no significant time trends.
在夏季或冬季对母马进行松果体切除后，这些动物与松果体完整的对照组在术后第一个繁殖季节的年度排卵日期并无差异，但在第二个季节，冬季接受松果体切除的母马排卵日期显著延迟，这表明松果体对季节性繁殖模式存在长期且明确的影响。将松果体切除的母马暴露于刺激性光周期下，未能提前首次年度排卵的平均日期，且与未接受刺激性光照的完整母马相似。结果表明，松果体切除会阻断对光刺激的反应能力。在完整母马中，黑暗期间血浆褪黑素浓度显著升高（P小于0.003），但松果体切除的母马未表现出显著的时间趋势。
