Sack R B, Froehlich J L
J Clin Microbiol. 1977 Jun;5(6):570-2. doi: 10.1128/jcm.5.6.570-572.1977.
With use of the rabbit intestinal loop model, heat-labile enterotoxins from 21 Escherichia coli strains isolated from a wide spectrum of patients with diarrheal diseases were all neutralized to high titer by two antisera prepared against enterotoxins of either E. coli or Vibrio cholerae. These findings suggest marked immunological similarity among heat-labile enterotoxins from a heterogenous group of E. coli.
利用兔肠袢模型,从患有各种腹泻疾病的患者中分离出的21株大肠杆菌产生的不耐热肠毒素,均被两种分别针对大肠杆菌或霍乱弧菌肠毒素制备的抗血清中和至高效价。这些发现表明,来自一组异源性大肠杆菌的不耐热肠毒素之间存在显著的免疫学相似性。