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[通过宫颈帽局部应用前列腺素E2引产]

[Local application of PGE2 by means of a cervical cap for the induction of labor].

作者信息

Grünberger W

出版信息

Wien Klin Wochenschr. 1982 Oct 29;94(20):561-4.

PMID:6963075
Abstract

206 pregnant women (36th to 42nd week of gestation) with low cervix scores were treated with an aqueous solution of PGE2 and NaCl applied peri-cervically by means of a portio adapter. In 169 cases (82%) labor was induced. In 29 patients (14.1%) the cervix was sufficiently ripened in order to allow successful induction by amniotomy. 11 patients (6.5%) were delivered by caesarean section, 7 (4.1%) by low forceps, all others delivered spontaneously. Time of delivery was short; no side effects were observed. Apgar scores and serum bilirubin levels of 30 neonates showed no differences to the control group consisting of 30 babies born after spontaneous onset of labor. In a second control group with labor induction by means of intravenous oxytocin infusion more than twice as many icteric neonates were found.

摘要

206名宫颈评分低的孕妇(妊娠36至42周)采用PGE2和NaCl水溶液,通过宫颈适配器在宫颈周围给药进行治疗。169例(82%)成功引产。29例(14.1%)宫颈充分成熟,得以通过人工破膜成功引产。11例(6.5%)行剖宫产,7例(4.1%)行低位产钳助产,其他均自然分娩。分娩时间短;未观察到副作用。30例新生儿的阿氏评分和血清胆红素水平与由30例自然发动分娩的婴儿组成的对照组无差异。在另一个通过静脉滴注催产素引产的对照组中,发现黄疸新生儿的数量是该组的两倍多。

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