Husslein P, Grünberger W, Huber J
Z Geburtshilfe Perinatol. 1980 Aug;184(4):267-74.
In 102 pregnant women with low cervix-scores (37th-42nd week of gestation) 1,25 mg PGE2 were applied to the cervix uteri by means of a portio-adapter. In 69 cases (67,6%) labor was induced. In 7 cases additional 0,75 mg PGE2 were instilled after 6h. in 9 women the portio-adapter was applied a second time the next day (in 4 of these even a third time). In 17 cases amniotomy was performed the next day. 11 patients (10,8%) were delivered by Cesarian section or low forceps, one women was discharged from hospital, all other delivered spontaneously. In 15 consecutive spontanous deliveries the pH of the V. umbilicalis was 7,29 +/- 0,12, the arterial pH 7,23 +/- 0,15. Intrauterine tocography revealed a uterine hyperactivity with no dystocie. When prostaglandins are applied to the cervix by means of a portio-adapter, the preparation of a gel-mixture can be avoided, an exact anatomic localisation of the therapeutic solutions is provided and the prostaglandins can be withdrawn at least partly in case of hyperstimulation. Another advantage of this from this induction is that the women are not confined to their bed until shortly before delivery.
在102例宫颈评分低的孕妇（妊娠37 - 42周）中，通过宫颈适配器将1.25毫克前列腺素E2应用于子宫颈。69例（67.6%）成功引产。7例在6小时后额外注入0.75毫克前列腺素E2。9名妇女在第二天再次使用宫颈适配器（其中4名甚至第三次使用）。17例在第二天进行了人工破膜。11例患者（10.8%）通过剖宫产或低位产钳分娩，1名妇女出院，其他所有患者均自然分娩。在连续15例自然分娩中，脐静脉pH值为7.29±0.12，动脉pH值为7.23±0.15。宫内宫缩图显示子宫活动过度但无难产。当通过宫颈适配器将前列腺素应用于子宫颈时，可以避免制备凝胶混合物，能实现治疗溶液的精确解剖定位，并且在子宫过度刺激的情况下可以至少部分撤回前列腺素。这种引产方法的另一个优点是，妇女在分娩前不久才需要卧床。
