Haapanen E J
Acta Med Scand Suppl. 1982;668:76-81.
Hemoperfusion was performed on 58 occasions to treat 48 patients with severe intoxication, of which 23 had taken on overdose of barbiturate or meprobamate. With one exception they all showed remarkable improvement during the treatment. In addition in many other intoxications patients greatly benefited from hemoperfusion, as with salicylate, paracetamol, quinidine, propranolol and mushroom intoxications. Hemoperfusion was of doubtful value or ineffective in intoxications due to tricyclic antidepressants, phenothiazine, digoxin and methanol. Four of the patients (7%) died. More side effects are seen during hemoperfusion than during hemodialysis. The disposable supplies of hemoperfusion are more costly than those for hemodialysis. Therefore if both kinds of treatment are equally effective, one has to prefer hemodialysis. Unfortunately intoxications exist, which do not respond to either hemoperfusion or hemodialysis.
进行了58次血液灌流治疗48例重度中毒患者，其中23例过量服用巴比妥类药物或眠尔通。除1例例外，他们在治疗期间均有显著改善。此外，在许多其他中毒情况中，患者也从血液灌流中受益匪浅，如水杨酸盐、对乙酰氨基酚、奎尼丁、普萘洛尔和蘑菇中毒。血液灌流对三环类抗抑郁药、吩噻嗪、地高辛和甲醇中毒的价值存疑或无效。4例患者（7%）死亡。血液灌流期间出现的副作用比血液透析期间更多。血液灌流的一次性耗材比血液透析的更昂贵。因此，如果两种治疗效果相同，人们更倾向于选择血液透析。不幸的是，存在对血液灌流或血液透析均无反应的中毒情况。
