Arvilommi H, Laatikainen A, Räsänen L
Acta Pathol Microbiol Scand C. 1978 Apr;86(2):59-62. doi: 10.1111/j.1699-0463.1978.tb02559.x.
We have shown earlier that unstimulated human lymphocytes in in vitro cultures produce migration inhibitory factor into the supernatant. The evidence of spontaneous lymphokine synthesis is strengthened further by this study, which demonstrates leukocyte chemotactic activity in these culture supernatants. The factor has a molecular weight of more than 5000 daltons, it resisted heating for 15 min at 100 degrees C, and showed maximum activity at dilution 1:4-1:8 of the supernatants.
我们之前已经表明，体外培养中未受刺激的人淋巴细胞会将迁移抑制因子分泌到上清液中。这项研究进一步加强了自发淋巴因子合成的证据，该研究证明了这些培养上清液中的白细胞趋化活性。该因子的分子量超过5000道尔顿，在100摄氏度下加热15分钟仍能抵抗，并且在上清液稀释1:4至1:8时表现出最大活性。
