人淋巴细胞因子的体外测定。干扰巨噬细胞移动抑制试验的移动刺激因子（MStF）的证据。
Assay of human lymphokines in vitro. Evidence for a migration stimulation factor (MStF) which interferes with the macrophage migration inhibition assay.
作者信息
Aaskov J G, Anthony H M
出版信息
Aust J Exp Biol Med Sci. 1976 Dec;54(6):527-39. doi: 10.1038/icb.1976.54.
When cultured in vitro, human lymphocytes produced a range of materials which were able to reduce the migration inhibitory effect of human macrophage migration inhibition factor (MIF) and in some cases stimulated macrophage migration to greater than control levels. In addition, lymphocytes stimulated with antigen or mitogen produced a lymphokine-like migration stimulation "factor". Detectable production of this factor occurred 24--48 h after antigen stimulation. The migration stimulation factor (MStF) (MW 50-250,000; pI 6-5) was not chemotactic and could be separated from migration inhibition and chemotactic factors by chromatography and iso-electric focussing.
在体外培养时，人淋巴细胞产生一系列物质，这些物质能够降低人巨噬细胞移动抑制因子（MIF）的移动抑制作用，在某些情况下还能刺激巨噬细胞移动至高于对照水平。此外，用抗原或有丝分裂原刺激的淋巴细胞产生一种类淋巴因子的移动刺激“因子”。抗原刺激后24 - 48小时可检测到该因子的产生。移动刺激因子（MStF）（分子量50 - 250,000；等电点6 - 5）无趋化性，可通过色谱法和等电聚焦与移动抑制因子和趋化因子分离。
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