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非霍奇金恶性淋巴瘤:使用细胞酶标记物“分型”的可靠性。与免疫标记物的比较(作者译)

[Non-Hodgkin's malignant lymphoma: reliability of "typing" using cyto-enzymatic markers. Comparison with immunological markers (author's transl)].

作者信息

Micheau C, Bernard A, Pujade E, Belpomme D, Carlu C, Clausse B

出版信息

Nouv Presse Med. 1980 Jan 12;9(3):167-70.

PMID:6965535
Abstract

Comparison between membrane markers and enzyme markers was made in 74 cases of non-Hodgkin's malignant lymphomas and a good correlation appears between both methods in order to distinct lymphomas into T and B origin. Enzyme markers are reliable and provide quickly made and easily interpretable documents. As far as T-lymphomas are concerned, three hydrolases namely acid phosphates e, acid esterase and B-glucuronidase give the same good results. As for B-lymphomas, a specific enzyme marker has to be found. Furthermore, typing of malignant lymphomas by enzymatic and/or immunologic methods appears to be quite better than from morphologic features such as convoluted or cleaved nuclei for example.

摘要

对74例非霍奇金恶性淋巴瘤患者进行了膜标志物和酶标志物的比较,两种方法之间存在良好的相关性,以便将淋巴瘤区分为T细胞来源和B细胞来源。酶标志物可靠,能快速生成且易于解读的文件。就T淋巴瘤而言,三种水解酶即酸性磷酸酶、酸性酯酶和β-葡萄糖醛酸酶都能给出同样良好的结果。至于B淋巴瘤,则必须找到一种特异性酶标志物。此外,通过酶学和/或免疫学方法对恶性淋巴瘤进行分型似乎比根据形态学特征(如核卷曲或核裂)进行分型要好得多。

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