Micheau C, Bernard A, Pujade E, Belpomme D, Carlu C, Clausse B
Nouv Presse Med. 1980 Jan 12;9(3):167-70.
Comparison between membrane markers and enzyme markers was made in 74 cases of non-Hodgkin's malignant lymphomas and a good correlation appears between both methods in order to distinct lymphomas into T and B origin. Enzyme markers are reliable and provide quickly made and easily interpretable documents. As far as T-lymphomas are concerned, three hydrolases namely acid phosphates e, acid esterase and B-glucuronidase give the same good results. As for B-lymphomas, a specific enzyme marker has to be found. Furthermore, typing of malignant lymphomas by enzymatic and/or immunologic methods appears to be quite better than from morphologic features such as convoluted or cleaved nuclei for example.
对74例非霍奇金恶性淋巴瘤患者进行了膜标志物和酶标志物的比较，两种方法之间存在良好的相关性，以便将淋巴瘤区分为T细胞来源和B细胞来源。酶标志物可靠，能快速生成且易于解读的文件。就T淋巴瘤而言，三种水解酶即酸性磷酸酶、酸性酯酶和β-葡萄糖醛酸酶都能给出同样良好的结果。至于B淋巴瘤，则必须找到一种特异性酶标志物。此外，通过酶学和/或免疫学方法对恶性淋巴瘤进行分型似乎比根据形态学特征（如核卷曲或核裂）进行分型要好得多。
