Rosati G, Granieri E, Pinna L, Aiello I, Tola R, De Bastiani P, Pirisi A, Devoto M C
Neurology. 1980 Mar;30(3):250-5. doi: 10.1212/wnl.30.3.250.
On the basis of previous epidemiologic studies, Parkinson disease was thought to be evenly distributed throughout the world. These studies, however, were conducted only on North European populations. The position with regard to the Mediterranean peoples was still unknown, and we therefore studied the frequency of Parkinson disease on the island of Sardinia, where some ethnic groups of the Mediterranean stock are represented. Based on 967 accepted cases, the prevalence 100,000 population on January 1, 1972, was 65.6; the average annual incidence for the period 1961 through 1971 was 4.9. These figures are one-half of the figures established for North Europeans. Our findings suggest racial differences in predisposition to Parkinson disease. Some Negroid features are present in Sardinians. If, as seems likely, Africans prove to be relatively unsusceptible to the disease, the risk for Sardinians and other Mediterranean ethnic groups might be intermediate between North Europeans and Africans.
基于以往的流行病学研究，帕金森病被认为在全球范围内分布均匀。然而，这些研究仅针对北欧人群开展。地中海地区人群的情况仍不明确，因此我们研究了撒丁岛帕金森病的发病频率，该岛有一些地中海血统的族群。基于967例确诊病例，1972年1月1日每10万人口中的患病率为65.6；1961年至1971年期间的年平均发病率为4.9。这些数字是北欧人相应数字的一半。我们的研究结果表明帕金森病易感性存在种族差异。撒丁岛人有一些黑人特征。如果事实证明非洲人相对不易患这种疾病，那么撒丁岛人和其他地中海族群患帕金森病的风险可能介于北欧人和非洲人之间。
