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左主干冠状动脉疾病的搭桥手术。术前主动脉内球囊反搏可减少围手术期心肌梗死。

Bypass surgery for left main coronary artery disease. Reduced perioperative myocardial infarction with preoperative intra-aortic balloon counterpulsation.

作者信息

Tahan S R, Geha A S, Hammond G L, Cohen L S, Langou R A

出版信息

Br Heart J. 1980 Feb;43(2):191-8. doi: 10.1136/hrt.43.2.191.

Abstract

From July 1975 to December 1977, 91 consecutive patients with left main coronary artery disease defined by cardiac catheterisation as greater than or equal to 50 per cent luminal narrowing underwent coronary bypass surgery. Prospective examination of the preoperative and postoperative clinical course of these patients was performed to determine the incidence of perioperative myocardial infarction. Intra-aortic balloon counterpulsation was instituted preoperatively in 35 patients, and these patients were classed as group A. Fifty-six patients did not receive the intra-aortic balloon pump and were classed as group B. Of 26 demographic, clinical, haemodynamic, and operative descriptors, only two were found to be significantly different between the two groups: the severity and the pattern of angina. Group A had a higher percentage of patients with class IV angina (80% vs 45%) and a greater proportion with unstable angina (37% vs 7%). Despite these differences group A patients had only a 3 per cent incidence of perioperative myocardial infraction while group B had a 23 per cent perioperative infarction rate. It is suggested that perioperative intra-aortic balloon counterpulsation can reduce the risk of perioperative myocardial infraction in patients with left main coronary artery stenosis.

摘要

1975年7月至1977年12月,连续91例经心导管检查确诊为左主干冠状动脉疾病(管腔狭窄大于或等于50%)的患者接受了冠状动脉搭桥手术。对这些患者术前和术后的临床病程进行前瞻性检查,以确定围手术期心肌梗死的发生率。35例患者术前进行了主动脉内球囊反搏,这些患者被归为A组。56例患者未接受主动脉内球囊泵,被归为B组。在26项人口统计学、临床、血流动力学和手术描述指标中,仅发现两组之间有两项指标存在显著差异:心绞痛的严重程度和类型。A组中IV级心绞痛患者的比例更高(80%对45%),不稳定型心绞痛患者的比例也更大(37%对7%)。尽管存在这些差异,但A组患者围手术期心肌梗死的发生率仅为3%,而B组的围手术期梗死率为23%。提示围手术期主动脉内球囊反搏可降低左主干冠状动脉狭窄患者围手术期心肌梗死的风险。

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