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65岁及以上患者接受主动脉冠状动脉搭桥手术的风险与益处。

Risks and benefits of aortocoronary bypass surgery in patients aged 65 years or more.

作者信息

Du Cailar C, Chaitman B R, Castonguay Y

出版信息

Can Med Assoc J. 1980 Apr 5;122(7):771-4.

Abstract

Between January 1970 and July 1978, 85 patients aged 65 years or more underwent aortocoronary bypass surgery at the Montreal Heart Institute. The mortality during the operation and the first 29 days thereafter was 12% overall, but was only 5% when the myocardium was protected by the use of cold cardioplegic solutions. Of the 75 patients who survived this period 7 (9%) had a perioperative transmural myocardial infarction. Nonfatal noncardiac complications were more common in these patients than in younger patients, but did not lead to permanent deficits. Three patients died after discharge from hospital, two of cardiac causes. Only one patient had a nonfatal myocardial infarction after discharge. The actuarial 5-year survival rate for all the patients was 80%. After a mean follow-up period of 30 months the condition of 94% of the patients was improved by at least one class of the New York Heart Association functional classification, and 68% were asymptomatic. It is concluded that aortocoronary bypass surgery can be performed in selected older patients with a relatively low in-hospital mortality and morbidity. Symptomatic improvement occurs in almost all such patients. Cardiac catheterization and aortocoronary bypass surgery should therefore be performed in selected older patients with severe angina that is refractory to optimum medical therapy.

摘要

1970年1月至1978年7月期间,85名65岁及以上的患者在蒙特利尔心脏研究所接受了主动脉冠状动脉搭桥手术。手术期间及术后前29天的总体死亡率为12%,但在使用冷心脏停搏液保护心肌时,死亡率仅为5%。在这一时期存活的75名患者中,有7名(9%)发生了围手术期透壁性心肌梗死。这些患者的非致命性非心脏并发症比年轻患者更常见,但未导致永久性缺陷。3名患者出院后死亡,2名死于心脏原因。只有1名患者出院后发生了非致命性心肌梗死。所有患者的精算5年生存率为80%。平均随访30个月后,94%的患者病情至少改善了纽约心脏协会功能分级的一个等级,68%的患者无症状。结论是,对于选定的老年患者,可以进行主动脉冠状动脉搭桥手术,住院死亡率和发病率相对较低。几乎所有此类患者的症状都有改善。因此,对于经最佳药物治疗仍难治的严重心绞痛的选定老年患者,应进行心导管检查和主动脉冠状动脉搭桥手术。

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